Progress of research on programmed cell death in infectious diseases
10.11816/cn.ni.2025-250050
- VernacularTitle:感染性疾病程序性细胞死亡研究进展
- Author:
Xiangpeng LI
1
;
Fengsen LI
;
Dan XU
;
Zheng LI
;
Jing WANG
;
Ling WANG
Author Information
1. 新疆医科大学第四临床医学院,新疆乌鲁木齐 830000
- Publication Type:Journal Article
- Keywords:
Programmed cell death;
Apoptosis;
Pyroptosis;
Necroptosis;
Pan-apoptosis
- From:
Chinese Journal of Nosocomiology
2025;35(17):2716-2720
- CountryChina
- Language:Chinese
-
Abstract:
Cell death is a fundamental phenomenon for organisms to maintain their basic morphology.When a pathogen infects a cell,the process of programmed cell death is activated,the lysed cells carrying the pathogen ac-tivate the immune response of the organism in the process of removing infected cells,thus exerting immune de-fense.The molecular mechanisms of the 4 types of cell death modes apoptosis,pyroptosis,necroptosis and pan-apoptosis as well as their effects on innate immune defense against microbial infections were mainly elaborated in the article,the interactions among the different programmed cell death pathways were briefly interpreted so as to provide new ideas for further study of pathogenic mechanisms of infectious diseases.