Progress of research on arenavirus infections and candidate drugs
10.11816/cn.ni.2025-250156
- VernacularTitle:沙粒病毒感染及候选药物研究进展
- Author:
Xin ZHANG
1
;
Shengqi WANG
;
Xuejun WANG
Author Information
1. 烟台大学药学院,山东烟台 264005;军事医学研究院生物信息中心,北京 100850
- Publication Type:Journal Article
- Keywords:
Arenavirus;
Viral hemorrhagic fever;
Lassa virus;
Antiviral drug;
Treatment
- From:
Chinese Journal of Nosocomiology
2025;35(17):2711-2715
- CountryChina
- Language:Chinese
-
Abstract:
Arenavirus infection in humans can lead to viral hemorrhagic fever,which is often fatal and poses a sig-nificant threat to public health.Currently,no effective therapeutic drugs or licensed vaccines are available for arenavirus infections,underscoring the urgency to strengthen the basic research on these viruses and develop novel antiviral therapies.This article summarizes the advancements of research on the structure,life cycle,pathogen-ic mechanisms,epidemiology,detection methods and newly discovered mammalian arenaviruses.Focusing on Las-sa virus,multiple candidate strategies for treatment of arenaviruses are explored,with expectations to provide ref-erences for the development of novel anti-arenaviral drugs.
