Treatment outcomes of patients with biliary sepsis and risk factors
10.11816/cn.ni.2025-251083
- VernacularTitle:胆源性脓毒症患者的预后及其危险因素
- Author:
Ximu ZHANG
1
;
Chengyong XU
1
;
Jianyuan YIN
1
;
Jie LIU
1
Author Information
1. 解放军总医院海南医院重症医学科,海南三亚 572000
- Publication Type:Journal Article
- Keywords:
Biliary sepsis;
Prognosis;
Death;
Risk factor
- From:
Chinese Journal of Nosocomiology
2025;35(18):2756-2759
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To summarize the characteristics of treatment outcomes of the patients with biliary sepsis and analyze the risk factors for death.METHODS The patients with biliary sepsis who were treated in Hainan Hospital of Chinese PLA General Hospital from Jun.2019 to Oct.2024 were retrospectively recruited as the re-search subjects and were divided into the survival group and the death group according to 28-day treatment out-comes after the diagnosis of sepsis.The baseline data and the intervention measures during the hospital stay were compared between the two groups of patients,the indexes with statistical significance were set as independent var-iables,and the death was set as dependent variable.Multivariate logistic regression analysis was performed for the risk factors for the 28-day death of the patients with biliary sepsis.RESULTS A total of 103 patients with biliary sepsis were finally included in the study,with 34(33.01％)cases in the death group,69(66.99％)cases in the survival group.Univariate analysis showed that the proportions of patients with no less than 65 years of age,shock and biliary tract obstruction,the average acute physiology and chronic health evaluation scoring system(A-PACHEⅡ)score and average sequential organ failure assessment(SOFA)score were remarkably higher in the death group than in the survival group(P＜0.05).The result of multivariate logistic regression analysis indicated that the advanced age,shock,biliary tract obstruction,APACHE Ⅱ score and SOFA score were the independent risk factors for the short-term death of the patients with biliary sepsis.CONCLUSIONS The risk of 28-day death of the patients with biliary sepsis is associated with the advanced age,shock,biliary tract obstruction,APACHE Ⅱscore and SOFA score.The combination of the above factors has high value in prediction of death.
