Conventional MRI and diffusion weighted imaging for differentiating soft tissue lymphoma and soft tissue sarcoma
10.13929/j.issn.1003-3289.2025.09.023
- VernacularTitle:常规MRI及弥散加权成像鉴别软组织淋巴瘤与软组织肉瘤
- Author:
Kai ZHANG
1
;
Yue DAI
;
Jie ZHOU
;
Jinge LI
;
Qing LIU
;
Juntong LIU
;
Juan TAO
;
Shaowu WANG
Author Information
1. 大连医科大学附属第二医院放射科,辽宁大连 116023
- Publication Type:Journal Article
- Keywords:
soft tissue neoplasms;
lymphoma;
sarcoma;
magnetic resonance imaging
- From:
Chinese Journal of Medical Imaging Technology
2025;41(9):1563-1567
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the value of conventional MRI and diffusion weighted imaging(DWI)for differentiating soft tissue lymphoma(STL)and soft tissue sarcoma(STS).Methods Conventional MRI and DWI data of 25 cases of STL(STL group)and 38 cases of STS(STS group)were retrospectively analyzed.MRI features being statistically different between groups were included in logistic regression analysis to screen the independent risk factors of STL and to evaluate the sensitivity,specificity and accuracy of their combination for predicting STL.Receiver operating characteristic curve was generated,the area under the curve(AUC)was calculated to assess the diagnostic efficacy of the mean apparent diffusion coefficient(ADCmean),the minimum apparent diffusion coefficient(ADCmin),the maximum apparent diffusion coefficient(ADCmax)values for distinguishing STL from STS.Results Slightly hyperintensity on T1WI,non-necrosis,involvement of multiple muscle groups and homogeneous enhancement were all independent risk factors of STL(all P＜0.05).The sensitivity,specificity and accuracy of their combination for predicting STL was 72.00％(18/25),89.47％(34/38)and 82.54％(52/63),respectively.ADCmean,ADCmin and ADCmax values of STL was(1.06±0.18)× 10-3,(0.77±0.14)×10-3 and(1.47±0.31)× 10-3mm2/s,respectively,all lower than those of STS([1.31±0.17]× 10-3,[1.02±0.23]× 10-3 and[1.64±0.16]× 10-3 mm2/s;t=-4.829--2.498,all P＜0.05).The AUC of ADCmean,ADCmin and ADCmax values and their combination for differential diagnosis of STL and STS was 0.845,0.844,0.683 and 0.877,respectively.Conclusion Conventional MRI features,including T1WI signal intensity,necrosis,involvement of multiple muscle groups and enhancement pattern,along with ADCmean and ADCmin values derived from DWI contributed to differentiating STL and STS.
