Research progress on reversal of atherosclerotic plaque by statins and combined lipid-lowering strategies
10.3760/cma.j.cn112434-20241230-00336
- VernacularTitle:他汀类药物及联合降脂策略逆转动脉粥样硬化斑块的研究进展
- Author:
Ruilong KANG
1
;
Yongzhi DENG
1
Author Information
1. 山西医科大学附属心血管病医院 山西省心血管病医院（研究所） 山西省心血管病临床医学研究中心心血管外科，太原 030024
- Publication Type:Journal Article
- From:
Chinese Journal of Thoracic and Cardiovascular Surgery
2025;41(9):570-576
- CountryChina
- Language:Chinese
-
Abstract:
Atherosclerosis is the most common cardiovascular disease, and dyslipidemia is the primary risk factor leading to atherosclerosis. Since the 21st century, the incidence rate of atherosclerosis in China is still on the rise, and the clinical treatment strategies of its patients need to be optimized urgently. Related studies have found that reducing cholesterol and alleviating inflammation can not only stabilize plaques, but also reverse them. With the development of imaging technology, more and more methods can be used to evaluate the distribution and burden of plaques, further guiding the adjustment of clinical lipid-lowering strategies. This article reviews the clinical application effects and latest research progress of monotherapy with statins and combined lipid-lowering strategies.
