Transvaginal ultrasound five-view method for diagnosing fetal congenital heart disease in early pregnancy of high-risk pregnancy
10.13929/j.issn.1003-3289.2025.09.019
- VernacularTitle:经阴道超声五切面检查法诊断孕早期高危妊娠胎儿先天性心脏病
- Author:
Qiuxia JIANG
1
;
Longyuan SHEN
;
Linjun CHEN
;
Qiuwen LI
;
Zhundun CAI
;
Guorong LYU
Author Information
1. 泉州市妇幼保健院(泉州市儿童医院)超声科,福建泉州 362000
- Publication Type:Journal Article
- Keywords:
heart defects,congenital;
fetus;
ultrasonography,prenatal
- From:
Chinese Journal of Medical Imaging Technology
2025;41(9):1544-1547
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the value of transvaginal ultrasound five-view method for diagnosing fetal congenital heart disease(CHD)in early pregnancy of high-risk pregnancy.Methods Totally 428 singleton fetuses at 11-13+6 weeks of gestation in high-risk pregnancies were prospectively enrolled.Fetal cardiac examinations were performed using two-dimensional grey scale imaging combined with CDFI via transabdominal ultrasound method,transvaginal ultrasound five-view method(upper abdominal transverse view,four-chamber view,three-vessel and trachea[3VT]view,ventricular outflow tract view and bilateral subclavian artery view)and transvaginal ultrasound two-view method(four-chamber view and 3VT view).Taken results of pregnant metaphase or late pregnancy fetal echocardiography,post-abortion pathology or postnatal neonatal echocardiography as gold standards,the diagnostic performances of the above 3 methods for diagnosing fetal CHD in early pregnancy were compared.Results CHD was diagnosed in 120(120/428,28.04%)fetuses.Transvaginal ultrasound five-view method made 11 false positives and 19 false negatives,with sensitivity,specificity,positive predictive value and negative predictive values for diagnosing fetal CHD in the first trimester of high-risk pregnancy of 84.17%,96.43%,90.18%and 93.99%,respectively,which were all significantly higher than of transvaginal ultrasound two-view method(70.83%,91.88%,77.27%and 88.99%)and transabdominal ultrasound method(72.50%,91.23%,76.32%and 89.49%;all P<0.05).Conclusion Transvaginal ultrasound five-view method could be used to effectively diagnose fetal CHD in the first trimester of high-risk pregnancy.