MR mDixon-Quant sequence for differentiating chylous and non-chylous pleural effusion
10.13929/j.issn.1003-3289.2025.09.014
- VernacularTitle:MR mDixon-Quant序列用于鉴别乳糜性与非乳糜性胸腔积液
- Author:
Huiyao LI
1
;
Ning ZHANG
1
;
Yunlong YUE
1
Author Information
1. 首都医科大学附属北京世纪坛医院医学影像科,北京 100038
- Publication Type:Journal Article
- Keywords:
chylothorax;
magnetic resonance imaging;
fat fraction
- From:
Chinese Journal of Medical Imaging Technology
2025;41(9):1522-1525
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the value of MR mDixon-Quant sequence for differentiating chylous and non-chylous pleural effusions.Methods MR mDixon-Quant sequence data of 28 cases of chylous pleural effusion(chylous group)and 18 cases of non-chylous pleural effusion(non-chylous group)were retrospectively analyzed.The average fat fraction(FF)value of pleural effusion and the average FF value of lipid component aggregation area within pleural effusion were measured based on FF maps,respectively.Pearson correlation analysis was used to evaluate the relationships of laboratory indicators and FF values.Receiver operating characteristic curve was plotted,and the area under the curve(AUC)was calculated to evaluate the diagnostic efficacy of FF values measured using the above 2 methods for distinguishing chylous and non-chylous pleural effusions.Results The average FF value of pleural effusion showed moderate or weak positive correlations with triglyceride,total cholesterol and albumin(r=0.727,0.661,0.445,all P＜0.01).Taken 0.95％as the optimal cutoff value,the sensitivity,specificity and AUC of the average FF value of pleural effusion for distinguishing chylous from non-chylous pleural effusions was 85.71％,100％and 0.962,respectively.The average FF value of lipid component aggregation area in pleural effusion exhibited strong,moderate and weak positive correlations with triglyceride,total cholesterol and albumin,respectively(r=0.815,0.739,0.492,all P＜0.01).Taken 0.87％as the optimal cutoff value,the sensitivity,specificity and AUC of the average FF value of lipid component aggregation area in pleural effusion for distinguishing chylous from non-chylous pleural effusions was 92.86％,100％and 0.982,respectively.No significant difference of diagnostic performance was found between these 2 methods(P=0.203).Conclusion MR mDixon-Quant sequence enabled non-invasive discrimination of chylous and non-chylous pleural effusions.The average FF value of lipid component aggregation area could more accurately reflect the fat component of pleural effusion.
