Clinical studies of Castleman's disease
10.3760/cma.j.cn112434-20240929-00234
- VernacularTitle:Castleman病的临床研究
- Author:
Feng WANG
1
;
Lizheng LYU
;
Yong YU
;
Xiaojun SUN
;
Shichao XU
;
Shuai LIU
;
Jixian WU
Author Information
1. 首都医科大学附属北京胸科医院微创诊疗中心，北京 101100
- Publication Type:Journal Article
- From:
Chinese Journal of Thoracic and Cardiovascular Surgery
2025;41(9):565-569
- CountryChina
- Language:Chinese
-
Abstract:
Castleman’s disease(CD) is a rare lymphoproliferative disorder that is classified based on the affected sites and pathological features. The pathogenesis of CD remains not fully understood and may be associated with viral infections, genetic abnormalities, and immunological factors. Clinically, CD is categorized into two types based on lymph node involvement: Unicentric Castleman Disease(UCD) and Multicentric Castleman Disease(MCD). Treatment options include surgery, chemotherapy, immunotherapy, and targeted therapy. This article summarizes recent advancements in the understanding of the pathogenesis, clinical characteristics, diagnosis, and treatment of CD, aiming to provide assistance for future clinical work.
