MR MAGiC sequence based on deep learning reconstruction for localizing epileptogenic focus of intractable epilepsy
10.13929/j.issn.1003-3289.2025.09.003
- VernacularTitle:基于深度学习重建MR MAGiC序列用于定位难治性癫痫致痫灶
- Author:
Jingjuan WANG
1
;
Huijuan XU
1
;
Yaqin HOU
1
;
Sudeep KHAREL
1
;
Chenyang YAO
1
;
Jie HU
1
;
Siqi ZHANG
1
;
Jie LU
1
Author Information
1. 首都医科大学宣武医院放射与核医学科,北京 100053;磁共振成像脑信息学北京市重点实验室,北京 100053
- Publication Type:Journal Article
- Keywords:
epilepsy;
deep learning;
image quality;
epileptogenic focus
- From:
Chinese Journal of Medical Imaging Technology
2025;41(9):1468-1472
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the application value of MR MAGiC sequence reconstructed based on deep learning reconstruction(DLR)for localizing epileptogenic focus of intractable epilepsy.Methods Fifty intractable epilepsy patients(epilepsy group)and 20 healthy controls(control group)were retrospectively collected.Brain MR MAGiC sequence was scanned,then traditional reconstruction(inverse Fourier transform)and DLR algorithm were performed to obtain MAGiC and MAGiC DLR images,respectively.The corresponding quantitative parameter maps were generated after post-processing,including T1 mapping,T2 mapping and proton density(PD)mapping.The subjective scores of noise,artifacts,structural clarity and overall quality were compared between two kinds of quantitative parameter images.The asymmetry index(AI)of quantitative parameters(T1,T2 and PD values)between the affected side and the contralateral side in epilepsy group,the contralateral side or the suspected epileptogenic focus in epilepsy group and HC group were calculated.Then epileptogenic focus were localized based on performance of MAGiC and MAGiC DLR corresponding quantitative parameter maps combining obtained AI of quantitative parameter values.According to surgical results,follow-up review,electroencephalogram or PET results,the accuracy of MAGiC and MAGiC DLR images for localizing epileptogenic focus was calculated.Results Compared with MAGiC quantitative parametric maps,noise of MAGiC DLR quantitative parametric maps reduced,while subjective scores of structure clarity and overall quality improved(all P＜0.05).The accuracy of MAGiC and MAGiC DLR images for localizing epileptogenic focus was 82.00％(41/50)and 88.00％(44/50),respectively.Conclusion MR MAGiC sequence based on DLR was beneficial for improving accuracy of localizing epileptogenic focus in intractable epilepsy.
