Association between platelet function and in-hospital mortality in patients with acute aortic dissection undergoing emergency surgical procedures
10.3760/cma.j.cn112434-20241119-00282
- VernacularTitle:急性Stanford A型主动脉夹层患者术前血小板功能与住院死亡相关性分析
- Author:
Haixiu XIE
1
;
Feng YANG
;
Xiaomeng WANG
;
Xing HAO
;
Feilong HEI
;
Junbo FENG
;
Fuhua HUANG
;
Xiaotong HOU
Author Information
1. 首都医科大学附属北京安贞医院心脏危重症中心体外循环与机械循环辅助科，北京 100029
- Publication Type:Journal Article
- Keywords:
Acute aortic dissection;
Thromboelastography;
Maximum amplitude;
Platelet function;
In-hospital mortality
- From:
Chinese Journal of Thoracic and Cardiovascular Surgery
2025;41(5):276-283
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the correlation between preoperative platelet function and in-hospital mortality in patients with acute Stanford A aortic dissection(ATAAD) undergoing emergency surgery.Methods:ATAAD emergency surgical patients who underwent preoperative thromboelastography(TEG) examination at three cardiovascular disease hospitals from January 2018 to December 2023 were consecutively selected in this study. The patients were divided into two groups according to whether the patient survived to discharge.Results:867 patients were included in this study. The in-hospital mortality was 11.2%(97 cases). Compared with the DG group(97 cases), the age, pericardial effusion volume, lactate concentration, and MA value of patients in the SG group(770 cases) were higher( P<0.001). Factors independently associated with in-hospital mortality were age(>60 years old), coronary hypoperfusion, pericardial effusion volume(>200.00 ml), and MA value(<60.6 mm). There was a correlation between MA value and in-hospital mortality( P=0.012), and the mediating effect between MA value and platelet count was not significant. Conclusion:There is a correlation between preoperative platelet function and in-hospital in ATAAD patients, and improving platelet function may be one of the important ways to improve the clinical prognosis of those patients.
