Incidence and Mortality of Colorectal Cancer in Zhejiang Cancer Registration Areas in 2021 and Trends from 2000 to 2021
10.11735/j.issn.1004-0242.2025.10.A005
- VernacularTitle:2021年浙江省肿瘤登记地区结直肠癌发病与死亡特征及2000-2021年变化趋势分析
- Author:
Yunfeng ZHU
1
;
Yi ZHOU
;
Tianjing GAO
;
Enning LU
;
Xiaofei CHEN
;
Zhongjie ZHU
;
Weimiao WU
;
Huizhang LI
;
Lingbin DU
;
Chunxiao JIANG
;
Yanfei QIU
Author Information
1. 海宁市中医院,海宁市肿瘤防治研究所,浙江海宁 314400
- Publication Type:Journal Article
- Keywords:
colorectal cancer;
incidence;
mortality;
trends;
Zhejiang
- From:
China Cancer
2025;34(10):783-791
- CountryChina
- Language:Chinese
-
Abstract:
[Purpose]To analyze the incidence and mortality of colorectal cancer in Zhejiang can-cer registration areas in 2021 and its temporal trends from 2000 to 2021.[Methods]Data from 22 cancer registries in Zhejiang Province in 2021 that met the quality standards were included.The crude incidence/mortality rate,age-standardized incidence/mortality rates by Chinese standard population(ASIRC/ASMRC)and by world standard population(ASIRW/ASMRW),and cumulative incidence(mortality)rate for 0~74 years old were calculated.Trends from 2000 to 2021 were ana-lyzed using the Joinpoint regression model by calculating the annual percentage change(APC)and average annual percentage change(AAPC).[Results]In 2021,the number of new colorectal cancer cases in Zhejiang cancer registration areas was 12 265,with 4 323 deaths.ASIRC and ASMRC were significantly higher in men(32.74/105 and 10.11/105)than those in women(20.78/105 and 5.99/105).Urban areas showed higher ASIRC and ASMRC(28.27/105 and 8.06/105)than rural areas(24.12/105 and 7.85/105).The age-specific incidence and mortality rates of colorectal cancer in Zhejiang Province showed an increasing trend with age,with a peak of 219.63/105 in the age group of 80~84 years old.The age-specific mortality rate peaked in the age group of 85 years old and above,with a peak of 199.65/105.From 2000 to 2021,ASIRC in Zhejiang Province showed an upward trend(AAPC=2.23%,P<0.001),ASMRC showed a marginal increase(AAPC=0.78%,P=0.067).[Conclusion]The incidence of colorectal cancer in Zhejiang Province had been on a continuous rise in the past 22 years,and health education and early screening should be empha-sized.