Progress in clinical diagnosis and treatment of lung cancer associated with cystic airspaces
10.3760/cma.j.cn112434-20240908-00216
- VernacularTitle:囊腔型肺癌的临床诊疗研究进展
- Author:
Jun CHENG
1
;
Chunfen GUO
;
Kun WU
;
Jiang GUO
;
Songtao KANG
;
Jian CHEN
Author Information
1. 湘潭市中心医院心胸外科,湘潭 411100
- Publication Type:Journal Article
- From:
Chinese Journal of Thoracic and Cardiovascular Surgery
2025;41(2):115-120
- CountryChina
- Language:Chinese
-
Abstract:
Lung cancer associated with cystic airspaces (LCCA) represents a less common subtype of lung cancer, possessing special morphological features and imaging characteristics. The disease often presents atypically in its early stages, frequently leading to misdiagnosis, especially in the variant with the feature of thin, smooth walls. Although there has been a significant body of research on LCCA in recent years, the focus has predominantly been on the pathogenesis, imaging classification and diagnosis, and the correlation between pathological types and imaging morphology. But, there is a limited number of research on surgical treatment strategies and subsequent management of this condition. Furthermore, postoperative consolidation and internal medical treatments for lung cancer patients necessitate integration with TNM staging, particularly the pathological stage. However, due to the unique morphology of LCCA, the primary tumor assessment (T staging) appears insufficient for accurately predicting the prognosis of the tumor. This article provides a comprehensive review of the etiology and pathogenesis of LCCA, its clinical presentation, imaging and morphological features, diagnosis and differential diagnosis, pathological and genetic mutation characteristics, treatment, and prognosis, thereby serving as a reference for the clinical diagnosis and treatment of LCCA.