Clinical observation of acupuncture combined with medication in the treatment of pediatric cough variant asthma
10.1007/s11726-025-1529-6
- VernacularTitle:针药并用治疗小儿咳嗽变异性哮喘临床观察
- Author:
Qiong ZHANG
;
Yinglin WANG
;
Chunyu LI
- Publication Type:Journal Article
- Keywords:
Acupuncture Therapy;
Acupuncture Medication Combined;
Interleukin-5;
Inflammatory Factors;
Nerve Growth Factor;
Substance P;
Cough Variant Asthma;
Child
- From:
Journal of Acupuncture and Tuina Science
2025;23(5):453-459
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe the clinical efficacy of acupuncture combined with Chinese medicine in the treatment of pediatric cough variant asthma(CVA)and the effects on clinical symptoms and inflammatory factor levels.Methods:A total of 136 children with CVA were randomly divided into a treatment group and a control group using the random number table method,with 68 cases in each group.Patients in the control group were treated with Chinese medicine,while patients in the treatment group were treated with Jiang Qi Ping Chuan(Qi-descending and asthma-relieving)acupuncture therapy in addition to the intervention of the control group.The clinical efficacy,cough severity,secondary symptom score,levels of inflammatory factors in induced sputum,and adverse reactions were observed after 4 weeks of treatment.Results:The total effective rate of the treatment group was higher than that of the control group,and the difference was statistically significant(P<0.05).The daytime cough score,nighttime cough score,and total cough score decreased significantly after treatment in both groups(P<0.05),and were notably lower in the treatment group than in the control group(P<0.05);the secondary symptom score and induced sputum inflammatory factor levels[interleukin(IL)-5,nerve growth factor(NGF),and substance P(SP)]decreased significantly after treatment in both groups(P<0.05),and were notably lower in the treatment group than in the control group(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion:The efficacy of acupuncture combined with Chinese medicine in the treatment of pediatric CVA is better than that of Chinese medicine alone;this combined method can rapidly relieve clinical symptoms and effectively inhibit inflammatory responses,with high safety.
