Retrospective Analysis on Clinical Efficacy of Xiazhu Sanjie Prescription in the Treatment of Pulmonary Nodules
10.19879/j.cnki.1005-5304.202502587
- VernacularTitle:夏术散结方治疗肺结节临床疗效回顾性分析
- Author:
Qinyan HONG
1
;
Xinyi ZHANG
;
Andong LI
;
Mingsheng LYU
;
Lei LI
;
Hongwu WANG
Author Information
1. 北京中医药大学东直门医院,北京 100700;北京中医药大学,北京 100029
- Publication Type:Journal Article
- Keywords:
pulmonary nodules;
traditional Chinese medicine;
Xiazhu Sanjie Prescription;
syndrome scores;
retrospective study
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2025;32(10):148-153
- CountryChina
- Language:Chinese
-
Abstract:
Objective To retrospectively analyze the clinical efficacy of Xiazhu Sanjie Prescription in treating pulmonary nodules.Methods A retrospective study was conducted on 58 patients of pulmonary nodules with spleen deficiency and excessive dampness syndrome who received Xiazhu Sanjie Prescription for 3 months or more at Dongzhimen Hospital,Beijing University of Chinese Medicine,from January 2021 to September 2024 were set as the observation group.Another 58 patients of pulmonary nodules with spleen deficiency excessive dampness syndrome who did not receive TCM intervention during the same period were selected as the control group.Basic information,TCM syndromes,and the diameters of pulmonary nodules on chest HRCT at the first and last visit were collected.Changes in nodule diameter,TCM syndrome scores,and TCM syndrome efficacy were compared between the two groups.Results Compared with the control group,the nodule diameter in the observation group significantly decreased(P<0.05),and the proportion of nodule disappearance or reduction was significantly higher than the control group(P<0.05).The TCM syndrome scores for symptoms such as excessive phlegm,fatigue,loss of appetite,pale complexion,irregular bowel movements,chest tightness,shortness of breath,heaviness of the head and limbs,and abdominal distention showed significant improvement in the observation group both compared to pre-treatment and the control group(P<0.05).The total effective rate of TCM syndromes in the observation group was 93.10%(54/58),while the control group was 17.24%(10/58).The observation group was significantly better than the control group(P<0.05).Conclusion Xiazhu Sanjie Prescription can reduce the diameter of pulmonary nodules to some extent and improve TCM syndromes in patients with pulmonary nodules.
