Discussion on Macrophage Polarization and Ulcerative Colitis Based on the Theory of"Yang Transforming Qi while Yin Constituting Form"
10.19879/j.cnki.1005-5304.202411679
- VernacularTitle:基于"阳化气,阴成形"理论探讨巨噬细胞极化与溃疡性结肠炎相关性
- Author:
Lu WANG
1
;
Dan LONG
1
;
Ying ZHU
1
Author Information
1. 湖南中医药大学第一附属医院,湖南 长沙 410000
- Publication Type:Journal Article
- Keywords:
ulcerative colitis;
macrophage polarization;
yang transforming qi;
yin constituting form;
harmony of yin and yang
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2025;32(10):27-31
- CountryChina
- Language:Chinese
-
Abstract:
Ulcerative colitis(UC)is a chronic inflammatory disease of the intestine with an unknown etiology and a long course of disease.In recent years,studies have shown that intestinal macrophages are the main participants in intestinal immune instability and intestinal inflammation,and intestinal inflammatory diseases are closely related to intestinal M1/M2 macrophage polarization imbalance."Yang transforming qi,while yin constituting form"is a highly summarized function and mechanism of yin and yang in the human body,and is fundamental to human life activities.The polarization of macrophages is highly consistent with the theory of"yang transforming qi,while yin constituting form".This article discussed the relationship between"yang transforming qi while yin constituting form"and macrophage polarization and UC,and believes that"insufficient transformation of qi by yang"is the basis of UC,"excessive formation by yin"is the standard of UC,"insufficient transformation of qi by yang"is mainly the deficiency of yang in the heart,spleen and kidney,and"excessive formation by yin"is about the stagnation of stasis,phlegm and dampness.The treatment methods are to warm the kidney yang to dissolve qi transpiration,warm the heart yang to clear the blood vessels,and support the spleen yang to transport water and dampness,remove blood stasis,resolve phlegm to dissipate clouding,so as to achieve the balance of yin and yang,which could provide references for the treatment of UC.