Early predictive value of triglyceride-glucose index and atherosclerosis index of plasma in moderate to severe hyperlipidemic acute pancreatitis
10.3969/j.issn.1673-9701.2025.26.001
- VernacularTitle:甘油三酯-葡萄糖指数、血浆致动脉粥样硬化指数对中重症高脂血症性急性胰腺炎的早期预测价值
- Author:
Yanwen YAO
1
;
Tao XUE
;
Sanxiong HUANG
;
Linhua YAO
Author Information
1. 湖州市第一人民医院消化内科,浙江湖州 313000
- Publication Type:Journal Article
- Keywords:
Triglyceride-glucose index;
Atherogenic index of plasma;
Systemic immune-inflammation index;
Hyperlipidemic acute pancreatitis
- From:
China Modern Doctor
2025;63(26):1-5
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the correlation between the triglyceride-glucose index(TyG),atherogenic index of plasma(AIP),systemic immune-inflammation index(SII),serum creatinine(SCr)and the severity of hyperlipidemic acute pancreatitis(HLAP).Methods A total of 156 HLAP patients admitted to Huzhou First People's Hospital from January 2020 to December 2024 were enrolled as subjects.They were divided into mild group(n=89)and moderately-severe/severe group(n=67)based on disease severity.Logistic regression analysis was used to identify independent risk factors.Spearman correlation analysis was used to examine the correlation between TyG,AIP,SCr,and HLAP severity.The predictive value of TyG,AIP,and SCr for HLAP were evaluated using receiver operating characteristic(ROC)curves.Results Levels of TyG,AIP,SII,and SCr were significantly higher in moderate-severe/severe group than in mild group(P＜0.05).Logistic regression analysis revealed that TyG,AIP,and SCr were independent risk factors for moderate-severe/severe HLAP(P＜0.05),whereas SII was not an independent risk factor.The severity of HLAP was positively correlated with early admission levels of TyG,AIP,and SCr.ROC curve analysis demonstrated that TyG showed superior diagnostic value compared to SCr and AIP.The combined indicators(SCr+AIP and SCr+TyG)outperformed single indicators in predictive value,with SCr+TyG exhibiting the highest predictive efficacy.Conclusion Early TyG,AIP,and SCr levels can serve as effective indicators for predicting disease severity in HLAP patients,and combined detection improves predictive accuracy.
