Correlation between intraoperative red blood cell transfusion and postoperative continuous renal replacement therapy in patients with acute type A aortic dissection
10.3760/cma.j.cn112434-20240613-00157
- VernacularTitle:急性A型主动脉夹层患者术中输注红细胞与术后接受连续肾脏替代治疗的相关性研究
- Author:
Longfei WANG
1
;
Xin LI
;
Wenjian JIANG
;
Ming GONG
;
Hongjia ZHANG
;
Yuyong LIU
Author Information
1. 首都医科大学附属北京安贞医院心脏外科中心，北京 100029
- Publication Type:Journal Article
- Keywords:
Aortic dissection;
Red blood cell transfusion;
Continuous renal replacement therapy
- From:
Chinese Journal of Thoracic and Cardiovascular Surgery
2024;40(12):744-749
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the correlation between intraoperative red blood cell (RBC) transfusion and postoperative continuous renal replacement therapy (CRRT) in patients with acute type A aortic dissection (ATAAD).Methods:Clinical data of 302 patients undergoing emergency surgery for ATAAD in the Department of Cardiac Surgery at Beijing Anzhen Hospital from September 2015 to October 2020 were retrospectively analyzed. Among them, 238 were males with a nean age of(46.3±10.0) years old; 64 were females with a mean age of (52.0±11.7) years old. Patients were divided into the CRRT group and the non-CRRT group based on whether they received CRRT postoperatively. Logistic regression analysis was used to investigate the correlation between intraoperative RBC transfusion and postoperative CRRT. Results:Forty-two patients (13.9%) required CRRT postoperatively. Univariate logistic regression analysis showed that intraoperative RBC transfusion increased the risk of postoperative CRRT ( OR=2.499, 95% CI: 1.266-4.470, P=0.008). However, after adjusting for other variables, multivariate logistic regression analysis showed that the association was not statistically significant ( OR=1.777, 95% CI: 0.583-5.417, P=0.312). Conclusion:The increased risk of postoperative CRRT in ATAAD patients due to intraoperative RBC transfusion is caused by confounding factors, and they are actually not significantly correlated.
