Analysis of the medication patterns of famous traditional Chinese medicine practitioners for the treatment of idiopathic membranous nephropathy based on data mining
10.3969/j.issn.1673-9701.2025.28.013
- VernacularTitle:基于数据挖掘探析名老中医治疗特发性膜性肾病的用药规律
- Author:
Sheng LI
1
;
Xiaoxia FENG
;
Lingzhi YU
;
Min CUI
;
Qin CHEN
Author Information
1. 浙江中医药大学中西医结合临床医学院,浙江 杭州 310012
- Publication Type:Journal Article
- Keywords:
Idiopathic membranous nephropathy;
Difficulty in treatment;
Medication pattern;
Data mining
- From:
China Modern Doctor
2025;63(28):58-63
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the medication patterns of famous traditional Chinese medicine practitioners in treating challenging aspects of idiopathic membranous nephropathy(IMN)based on data mining.Methods Medical cases meeting the inclusion and exclusion criteria were collected.Statistical analysis of syndrome patterns,herb frequency,association rules,and cluster analysis were conducted for key challenges,including disease duration ≥ 1 year,renal function impairment,hypoalbuminemia,and hypertriglyceridemia.Results A total of 128 medical cases were included.Spleen-kidney deficiency syndrome was identified as the most common pattern.Based on herb frequency and association rule analysis,Huangqi,Baizhu,Fuling,Danggui,Danshen were the most frequently used in prescription.Cluster analysis revealed core herbal groupings primarily based on classical formulas such as Zhenwu decoction,Shenling Baizhu powder,and Shuilu Erxian dan.Conclusion In the medical cases addressing treatment challenges,the syndrome patterns were predominantly characterized by spleen-kidney deficiency.Core medications included Huangqi,Baizhu,Fuling,Danggui and Danshen.The treatment emphasizes strengthening invigorating spleen and kidney,with variations in medication patterns based on disease duration and complications.
