Clinical efficacy of individual molded Ozaki autologous pericardial aortic valve reconstruction
10.3760/cma.j.cn112434-20240407-00098
- VernacularTitle:个体模具化Ozaki自体心包主动脉瓣重建修复术的疗效观察
- Author:
Fan ZHANG
1
;
Haibo ZHANG
1
;
Jiangang WANG
1
;
Jie HAN
1
;
Shengyu WANG
1
Author Information
1. 首都医科大学附属北京安贞医院心脏外科中心,北京 100029
- Publication Type:Journal Article
- Keywords:
Aortic valve replacement;
Autologous pericardium molded valve;
Clinical efficacy
- From:
Chinese Journal of Thoracic and Cardiovascular Surgery
2024;40(12):732-735
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the clinical efficacy of individual molded Ozaki autologous pericardial aortic valve reconstruction in the treatment of aortic valve disease.Methods:This study adopted the method of retrospective statistical analysis. A total of 32 patients with complete follow-up of autologous pericardial aortic valve reconstruction were all included in the cardiac surgery department of Beijing Anzhen Hospital from 2015 to 2021. The basic clinical data, the echocardiography results before or after operation of the patients were collected and recorded. All patients were followed up in October 2023, the survival status and the echocardiography results in 12 months were recorded.Results:There was no death and operation related complications during the postoperative hospitalization. The results of postoperative esophageal echocardiography showed that the degree of valve regurgitation was significantly reduced in all patients. The echocardiographic results showed that the maximum aortic velocity[(172.00±49.54)cm/s vs. (221.90±114.90)cm/s, P=0.026], transvalvular gradients of aortic valve[(17.23±10.39)mmHg vs.(40.58±30.75)mmHg, P<0.01], and end diastolic diameter of left ventricular[(48.81±7.60 )mm vs.(58.45±7.56)mm, P<0.001]were significantly reduced after operation( P<0.05). 26 patients were followed up and survival, and no moderate to severe aortic regurgitation occurred in these patients. The echocardiogram results showed the ejection fraction was 0.60±0.15, end diastolic diameter of left ventricular was(37.15±8.40)mm, the maximum aortic velocity was(158.00±37.42)cm/s, transvalvular gradients of aortic was(18.95±14.57)mmHg. Conclusion:The clinical effect of individual molded Ozaki autologous pericardial aortic valve reconstruction technique in the treatment of aortic valve stenosis or aortic valve insufficiency is better, showed that this method can significantly improve the valve hemodynamics.