Elimination of hepatitis B: what are the strengths and limitations of laboratory medicine
10.3760/cma.j.cn114452-20240729-00409
- VernacularTitle:消除乙型肝炎病毒危害：检验医学的“足”与“不足”
- Author:
Qishui OU
1
;
Ya FU
1
;
Can LIU
1
Author Information
1. 福建医科大学附属第一医院检验科 福建省检验医学重点实验室 福建医科大学附属第一医院滨海院区国家区域医疗中心福建医科大学基因诊断研究中心，福州 350005
- Publication Type:Journal Article
- Keywords:
Clinical laboratory techniques;
Hepatitis B virus;
Chronic hepatitis B;
Biomarker
- From:
Chinese Journal of Laboratory Medicine
2025;48(1):1-7
- CountryChina
- Language:Chinese
-
Abstract:
Laboratory medicine plays a crucial role in the diagnosis of hepatitis B virus (HBV) infection, primarily through the detection of HBV markers and diagnostic markers of liver disease progression. HBV markers can be categorized into classical and novel types. Diagnostic markers of liver disease progression related to HBV infection are mainly associated with hepatitis, liver fibrosis, and liver cancer. Currently, there are unresolved issues in laboratory medicine regarding the management of chronic HBV infection. Addressing these issues is essential to achieve the goal of "eliminating hepatitis B related public health threat in our country". This article summarizes the research progress and clinical applications of HBV markers and liver disease progression diagnostic markers (the "strengths" of laboratory medicine), while also contemplates the new requirements posed by the elimination of hepatitis B on laboratory medicine (the "limitations"). A commentary on the "strengths" and "limitations" of laboratory medicine in the context of hepatitis B elimination is provided for reference by clinicians and laboratory professionals.
