Prevalence and risk factors of food allergies among children in North China grassland: a cross-sectional study based on Zhangbei County, Hebei Province
10.3760/cma.j.cn112150-20250614-00550
- VernacularTitle:华北草原地区儿童食物过敏的患病率及危险因素分析：基于河北省张北县的横断面研究
- Author:
Yang LIU
1
;
Yanlei CHEN
;
Yaojun PANG
;
Ruijuan ZHANG
;
Haiyun SHI
;
Weiting JIN
;
Wenhua MING
;
Ye WANG
;
Zilu CHENG
;
Tingting MA
;
Xueyan WANG
Author Information
1. 首都医科大学附属北京世纪坛医院变态反应科，北京 100038
- Publication Type:Journal Article
- Keywords:
Food allergy;
Children;
Self-reported;
Prevalence;
Risk factor
- From:
Chinese Journal of Preventive Medicine
2025;59(10):1725-1733
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To determine the prevalence of self-reported food allergies among children in the grasslands of North China and to analyze its associated risk factors.Methods:In this study, a cross-sectional epidemiological survey method was used to select children under 14 years old by multi-stage, stratified and random cluster sampling in the grassland ecological area of Zhangbei County, Hebei Province, China from May to July 2018. Face-to-face questionnaires were administered to gather food allergy-related information from the participants. Multivariate logistic regression analysis was used to analyze the risk factors associated with self-reported food allergy.Results:A total of 2 086 children completed the survey. The prevalence of self-reported food allergies was 22.0%(459/2 086). The prevalence of multiple food allergies (≥3 types) was 3.1%(64/2 086) versus 16.3% (341/2 086) for a single food allergy among all children. Mango allergy (6.1%, 127/2 086) was the most common, followed by peach allergy (4.1%, 85/2 086). Children who reported food allergies had a significantly higher prevalence of all 4 atopic disorders (eczema, asthma, allergic rhinitis, and allergic conjunctivitis than those without food allergies(35.73% vs. 20.65%, 5.88% vs. 2.77%, 17.86% vs. 7.38%, 16.78% vs. 10.45%, χ2 =44.663 1, 10.434 3, 45.038 3, 13.728 4, all P<0.001).Significantly associated risk factors of food allergy were found to be pollen allergy ( OR: 2.29; 95% CI: 1.80-2.92) and drug allergy ( OR: 1.53; 95% CI: 1.12-2.09). Conclusions:The prevalence of self-reported food allergies among children in the Zhangbei County area of the North China Grassland was relatively high. Pollen allergy and drug allergy are major risk factors.
