Clinical characteristics, diagnosis, and treatment strategies for drug-induced autoimmune hepatitis
10.3760/cma.j.cn501113-20250507-00176
- VernacularTitle:药物诱导的自身免疫样肝炎的临床特点和诊治策略
- Author:
Fei LI
1
;
Qidi ZHANG
1
;
Lungen LU
1
Author Information
1. 上海交通大学医学院附属第一人民医院消化内科，上海 200080
- Publication Type:Journal Article
- Keywords:
Drug-induced liver injury;
Autoimmune hepatitis;
Diagnosis;
Differential diagnosis;
Drug-induced autoimmune-like hepatitis
- From:
Chinese Journal of Hepatology
2025;33(7):633-636
- CountryChina
- Language:Chinese
-
Abstract:
Drug-induced liver injury (DILI) is an important adverse drug reaction with diverse clinical manifestations. Drug-induced autoimmune-like hepatitis (DI-ALH) is a special type of DILI possessing clinical, serological, and histological features similar to autoimmune hepatitis (AIH). However, there are significant differences between DI-ALH and AIH in terms of treatment plan, course of disease, and prognosis; therefore, differential diagnosis between DI-ALH and AIH is crucial. This article summarizes the epidemiology, pathogenesis, clinical characteristics, diagnosis and differential diagnosis, treatment, and prognosis of DI-ALH and analyzes the existing problems in order to provide guidance for the diagnosis, treatment, and future research direction.
