Research progress on early-stage primary biliary cholangitis accompanied by portal hypertension
10.3760/cma.j.cn501113-20250505-00172
- VernacularTitle:早期原发性胆汁性胆管炎伴门静脉高压的研究进展
- Author:
Lin MA
1
;
Li SHEN
1
;
Shuxiang LI
1
;
Weijia DUAN
1
;
Jidong JIA
1
;
Hong YOU
1
Author Information
1. 首都医科大学附属北京友谊医院肝病中心 消化健康全国重点实验室 国家消化系统疾病临床医学研究中心，北京 100050
- Publication Type:Journal Article
- Keywords:
Primary biliary cholangitis;
Portal hypertension;
Diagnosis;
Therapeutic
- From:
Chinese Journal of Hepatology
2025;33(7):628-632
- CountryChina
- Language:Chinese
-
Abstract:
Primary biliary cholangitis (PBC) is a type of autoimmune liver disease characterized by chronic intrahepatic cholestasis. Although portal hypertension is a common complication in patients with cirrhotic PBC, portal hypertension and its related complications can occur in the early stage of the disease, that is, before the cirrhosis onset. Therefore, early identification and long-term management are of great significance to reduce the occurrence of portal hypertension and decompensation events and improve long-term prognosis in patients with PBC. This paper focuses on the epidemiology, pathophysiological mechanism, clinical characteristics, non-invasive diagnosis, and treatment strategies for portal hypertension in early-stage PBC patients.
