The impact and management strategy of Conflict of Interest related to clinical research
10.3760/cma.j.cn113565-20240301-00062
- VernacularTitle:临床研究相关利益冲突的影响和管理对策
- Author:
Yingshuo HUANG
1
;
Yue LI
1
;
Lihan XING
1
;
Xu ZUO
1
;
Shuilong GUO
1
Author Information
1. 首都医科大学附属北京友谊医院科技处，北京 100050
- Publication Type:Journal Article
- Keywords:
Conflict of Interest;
Clinical research;
Medical ethics;
Scientific research integrity
- From:
Chinese Journal of Medical Science Research Management
2025;38(2):140-144
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the management strategies of conflicts of interest(COI) by analyzing the definition, manifestations, and implications of COI related to clinical research.Methods:This study summarized the definitions and types, manifestations, and implications of different groups of COI in clinical research. It explored the management response of medical institutions to the COI related to clinical research.Results:Conflicts of Interest could be divided into economic and non-economic conflicts of interest, showing different manifestations in different groups. COI occurs in a variety of links involved in clinical research, and the overall disclosure ratio of COI is low, which might have adverse effects on institutions, investigators, clinical research quality, and subjects.Conclusions:COI management should be implemented by strengthening the construction of the COI management system, strictly following the principle of public disclosure, and strengthening education and training, to improve the quality and credibility of clinical research.
