The current situation and prospect for the diagnosis and treatment of metanephric adenoma
10.3760/cma.j.cn112330-20240607-00257
- VernacularTitle:后肾腺瘤诊治的现状和展望
- Author:
Wujie CHEN
1
;
Jun GU
;
Enxiu LUO
;
Mengdi ZHOU
;
Yinglong HUANG
;
Haohao LI
;
Haidan LI
;
Zhiyong TAN
;
Haifeng WANG
;
Mingxia DING
Author Information
1. 昆明医科大学第二附属医院泌尿外科，昆明 650000
- Publication Type:Journal Article
- Keywords:
Metanephric adenoma;
Diagnosis;
Treat
- From:
Chinese Journal of Urology
2025;46(6):472-475
- CountryChina
- Language:Chinese
-
Abstract:
Metanephric adenoma is a rare renal epithelial tumor with a low incidence and lack of specific clinical manifestations，resulting in a lack of uniformity in clinical understanding and treatment. Its etiology and pathogenesis are still unclear，and it may be related to the abnormal number and structure of chromosomes 2，7，and 17，as well as mutations in genes such as BRAF V600E，NF1，and NOTCH1，etc. There may be a transformed relationship between this tumor and Wilms’ tumor and papillary renal cell carcinoma. For diagnosis，it has diverse but non-specific clinical manifestations，and it is difficult to accurately differentiate it from other tumors in the imaging examination，and the confirmation of diagnosis relies on pathological and immunohistochemical staining. Treatment is mainly based on surgery to preserve the renal unit，such as partial nephrectomy，etc.，but the difficulty of preoperative diagnosis often leads to over-treatment，and there is a lack of standardized treatment protocols for metastatic posterior renal adenoma. The aim of this article is to provide a reference for the in-depth understanding of posterior renal adenomas and to optimize the clinical diagnosis and treatment strategies.
