Research progress of miRNAs in peripheral blood as biomarkers of ionizing radiation damage

VernacularTitle:外周血miRNAs作为电离辐射损伤生物标志物的研究进展
Author: Ruixia ZHOU ¹ ; Shuang LI ¹
Author Information

1. 中国疾病预防控制中心辐射防护与核安全医学所　辐射防护与核应急中国疾病预防控制中心重点实验室，北京　100088
Publication Type:Journal Article
Keywords: miRNAs; Radiation damage; Biomarkers
From: Chinese Journal of Radiological Medicine and Protection 2025;45(9):920-924
CountryChina
Language:Chinese
Abstract: In the case of acute radiation-induced damage, rapidly and accurately assessing the exposure dose using biomarkers is crucial to medical treatment. In recent years, with the application of technologies such as metabolomics, immunomics, and genomics, more radiation biomarkers have emerged based on gene transcription markers and radiation metabolites. MicroRNAs (miRNAs), a type of molecular biomarkers, have demonstrated great potential in radiation damage assessment due to their simplicity of tests and high throughput. This review summarized the biological characteristics of miRNAs and advances in research on peripheral blood miRNAs as biomarkers of radiation-induced damage.