Expert consensus on clinical treatment of acute radiation syndrome from external irradiation
10.3760/cma.j.cn112271-20241209-00468
- VernacularTitle:外照射急性放射病临床救治专家共识
- Author:
Li LIANG
1
;
Long YUAN
;
Changlin YU
;
Qingjie LIU
;
Yulong LIU
;
Wenfeng YANG
;
Jin WANG
;
Weixu HUANG
;
Ying LIU
;
Cuiping LEI
;
Huifang CHEN
;
Ximing FU
;
Baoshan CAO
;
Mopei WANG
;
Zhaohui ZHANG
;
Yu XIAO
;
Yamei CHEN
;
Quanfu SUN
Author Information
1. 北京大学第三医院肿瘤化疗与放射病科，北京 100191
- Publication Type:Journal Article
- Keywords:
External irradiation;
Acute radiation sickness;
Dose estimation;
Diagnosis;
Treatment
- From:
Chinese Journal of Radiological Medicine and Protection
2025;45(9):827-839
- CountryChina
- Language:Chinese
-
Abstract:
China emerges as a major country in nuclear energy development and the application of nuclear and radiologic technology. The diagnosis and treatment of acute radiation syndrom (ARS) caused by external irradiation represent a core function in the country′s medical rescue of nuclear and radiological emergencies. Clinically, ARS manifests hematopoietic, gastrointestinal, cutaneous, and central nervous system syndromes, with specific clinical manifestations, signs, severity, and prognosis strongly correlated with radiation dose. China has established a number of national and provincial centers for treating radiation-induced damage. Nevertheless, most medical staff have limited experience in ARS treatment. This consensus presents a summary of recent experience in treating ARS of China. In combination with recommendations from international organizations such as the World Health Organization (WHO), this consensus proposes key evidence of critical clinical issues of ARS, covering all links in the rescue of external irradiation-induced ARS. Initially, clinical diagnosis, syndromes, and severe degrees should be determined based on clinical symptoms and dose estimates. It is necessary to normalize clinical treatment measures for hematopoietic recovery, gastrointestinal injury treatment, infection control, symptomatic treatment, and multi-organ function preservation. To this end, this consensus offers cautions. This consensus provides principles of treatment with traditional Chinese medicine, psychological intervention, and follow-up. Additionally, it highlights multidisciplinary collaboration. It is recommended that this consensus be applied in relevant treatment centers.
