Current status of radiation sources, meterage and protection in X-ray FLASH radiotherapy
10.3760/cma.j.cn112271-20251024-00370
- VernacularTitle:X射线FLASH放射治疗的射线来源、计量与防护研究现状
- Author:
Dai WU
1
;
Yiwei YANG
;
Yi ZHANG
;
Yinghong TANG
;
Xulin HU
;
Qingqing WANG
Author Information
1. 中国工程物理研究院应用电子学研究所,绵阳 621900
- Publication Type:Journal Article
- Keywords:
FLASH radiotherapy;
X-rays;
Radiation sources;
Dosimetry
- From:
Chinese Journal of Radiological Medicine and Protection
2025;45(11):1041-1046
- CountryChina
- Language:Chinese
-
Abstract:
International studies have established that electrons, X-rays, protons, and heavy ions can all be utilized in ultra-high dose-rate radiotherapy. Among these modalities, megavoltage X-ray ultra-high dose-rate radiotherapy holds particularly broad clinical promise. With its long-term expertise in high-intensity pulsed radiation sources, the Institute of Applied Electronics at the China Academy of Engineering Physics has pioneered global solutions for generating and measuring megavoltage X-rays ultra-high dose-rate radiotherapy, positioning China at the forefront of this field. Herein, we review the development history, current status, and future trends in ultra-high dose-rate X-ray generation, measurement, and protection. The insights provided aim to serve as a reliable reference for clinical and preclinical research, equipment development, and standardization, thereby enabling more precise and reliable megavoltage ultra-high dose-rate X-ray production and measurement. We hope this work will significantly support further research and clinical translation of ultra-high dose-rate radiotherapy technology.