Research progress on application value of robot-assisted radical prostatectomy in high-risk prostate cancer
10.3760/cma.j.cn112330-20250218-00061
- VernacularTitle:机器人辅助根治性前列腺切除术在高危前列腺癌中应用价值的研究进展
- Author:
Qi CAI
1
;
Weijun FU
1
Author Information
1. 解放军总医院第三医学中心泌尿外科医学部，北京 100039
- Publication Type:Journal Article
- Keywords:
High-risk prostate cancer;
Robot-assisted radical prostatectomy;
Lymph node dissection;
Retzius spiring robot-assisted radical prostatectomy;
PSMA radio-g
- From:
Chinese Journal of Urology
2025;46(6):476-480
- CountryChina
- Language:Chinese
-
Abstract:
High-risk prostate cancer（HRPC）faces severe challenges in clinical management due to its strong invasiveness and easy relapse after surgery. Robot-assisted radical prostatectomy（RARP）has gradually become the core method of HRPC multimodal treatment due to its minimally invasive，precise operation，and perioperative advantages. In this article，the author systematically summarizes the application value of RARP in HRPC：Studies show that RARP may have advantages in reducing intraoperative bleeding and the positive margin rate. Compared with traditional open surgery，its trend of reducing postoperative biochemical relapse rate may be related to survival benefits. The new surgical techniques as Single-Site RARP and Retzius-sparing RARP（RS-RARP）further optimize urinary control and sexual function protection，while PSMA radio-guided surgery（PSMA-RGS）improves tumor clearance by accurately locating micrometastasis during surgery. Artificial intelligence technology significantly improves surgical precision，safety，and efficiency by accurately segmenting lesions，predicting risks，providing real-time navigation，and optimizing surgical programs. However，the clinical value，timing of adjuvant therapy，and individualized strategies of lymph node dissection still require high-quality evidence support. Future research on RARP in high-risk patients needs to focus on the integration of precise risk stratification，molecular imaging navigation，and artificial intelligence technology to achieve a leapfrog development from survival benefits to improved quality of life.
