Application of the ArcherQA 3D dosimetric verification system in dosimetric verification of VMAT plans
10.3760/cma.j.cn112271-20240924-00379
- VernacularTitle:ArcherQA三维剂量验证系统在VMAT计划剂量验证的应用
- Author:
Jieping ZHOU
1
;
Ning GAO
;
Zhongyu QI
;
Qiang REN
;
Xi PEI
;
Xie XU
;
Aidong WU
Author Information
1. 中国科学技术大学附属第一医院（安徽省立医院） 放疗科，合肥 230031
- Publication Type:Journal Article
- Keywords:
Monte Carlo algorithm;
Dosimetric verification;
Volumetric Modulated Arc Therapy
- From:
Chinese Journal of Radiological Medicine and Protection
2025;45(6):551-557
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To rapidly and accurately detect volumetric modulated arc therapy (VMAT) plans with potentially inaccurate radiation doses.Methods:The measurement-based dosimetric verification result of 196 VMAT plans obtained using ArcCHECK phantoms were retrospectively collected. Independent dosimetric calculation and verification were conducted for these plans using the ArcherQA system based on a fast Monte Carlo algorithm. The gamma passing rates of dosimetric verification using ArcCHECK phantom and the ArcherQA system were compared, followed by their correlation analysis and linear regression fitting. The ArcherQA system′s gamma passing rate threshold used to detect positive dosimetric verification result obtained using ArcCHECK phantoms, as well as the specificity of the detection, were calculated. Based on this gamma passing rate threshold, another 50 VMAT plans were selected as a test set to assess the ArcherQA system′s ability to detect positive measurement-based dosimetric verification result.Results:The average gamma passing rates for the dosimetric verification of the VMAT plans using the ArcherQA system and ArcCHECK phantoms were 97.28% and 96.57% (3%/3 mm, TH=10%), respectively. Both rates had a correlation coefficient of 0.71 ( P < 0.01) and a linear fitting coefficient of 0.54 ( R2=0.51). When the gamma passing rate for dosimetric verification using ArcCHECK phantoms was set at 90% (3%/2 mm, TH=10%), the gamma passing rate threshold for dosimetric verification using the ArcherQA system should be adjusted to 94.8% to detect all VMAT plans with positive dosimetric verification result obtained using ArcCHECK phantoms, with a specificity of 67.8%. Using this threshold, the ArcherQA system detected all VMAT plans in the test set for which ArcCHECK phantom-based measurement yielded positive dosimetric verification result. Conclusions:By determining an appropriate gamma passing rate threshold, the ArcherQA system can rapidly and accurately detect VMAT plans with potentially inaccurate doses, thus ensuring treatment accuracy and improving work efficiency.
