Research progress of pelvic lymph node dissection in patients with localized intermediate- and high-risk prostate cancer
- VernacularTitle:局限性中高危前列腺癌患者行盆腔淋巴结清扫的研究进展
- Author:
Zhiqiang CHEN
1
;
Zhuoran LI
1
;
Jin LUO
1
;
Qiwei LIU
1
;
Yuqi JIA
1
;
Jinqiao LI
1
;
Qiming YANG
1
;
Yujie DONG
1
;
Shaoxi NIU
1
;
Baojun WANG
1
Author Information
- Publication Type:Journal Article
- Keywords: Prostatic neoplasms; Carcinoma; localized; intermediate- and high-risk; pelvic lymph node dissection
- From: Chinese Journal of Urology 2025;46(5):397-400
- CountryChina
- Language:Chinese
- Abstract: The strategy of pelvic lymph node dissection in patients with localized intermediate- and high-risk prostate cancer（PCa）has been one of the research hotspots in recent years. This review synthesizes recent progress in clinical，diagnostic imaging and immunological aspects of pelvic lymph node dissection.It is found that the detection rate of metastatic lymph nodes in patients with localized intermediate-risk PCa is relatively low，and the survival benefit after dissection is not significant. PSMA PET/CT examination can be used instead of lymph node dissection for staging. Extended lymph node dissection in patients with localized high-risk PCa can achieve a higher detection rate of metastatic lymph nodes and possible survival benefits. However，excessive lymph node dissection can weaken the response ability to immunotherapy. The strategy for pelvic lymph node dissection in patients with localized intermediate-high-risk PCa needs further study.
