Advances in research on the application of magnetic ferrite nanoparticles in radiotherapy

VernacularTitle:磁性铁氧体纳米颗粒应用于放疗中的研究进展
Author: Liang WANG ¹ ; Hailei LIN ; Yanqin JI
Author Information

1. 中国疾病预防控制中心辐射防护与核安全医学所　辐射防护与核应急中国疾病预防控制中心重点实验室，北京　100088
Publication Type:Journal Article
Keywords: Magnetic ferrite nanoparticles; Malignant tumors; Radiotherapy; Radiosensitivity
From: Chinese Journal of Radiological Medicine and Protection 2025;45(1):74-79
CountryChina
Language:Chinese
Abstract: Radiation-induced adverse reactions in organs at risk(OAR) is recognized as a significant factor limiting doses to clinical target volumes(CTV). Magnetic ferrite nanoparticles, distinguished by their unique physicochemical properties such as ease of modification and high biocompatibility, have been extensively investigated in the biomedical field. This article reviews the latest advances in research on the application of magnetic ferrite nanoparticles in radiotherapy, focusing on their magnetothermal effect, dose enhancement effect, promotion of ferroptosis, regulation of the cell cycle, and improvement in image-guided quality. Furthermore, this article provides an outlook for future research.