Research trends and hotspots of bupivacaine liposomes: bibliometric analysis from 1994 to 2023
10.3760/cma.j.cn131073-20240924-00613
- VernacularTitle:布比卡因脂质体的研究趋势和热点：1994—2023年文献计量学分析
- Author:
Yuxiang MENG
1
;
Sumin YUAN
1
;
Zijie LING
1
;
Li ZHANG
1
;
Zhibiao XU
1
;
Yuyun LIU
1
;
Chenyang SHI
1
;
Hengrui ZHANG
1
;
Yang NIU
1
;
Su LIU
1
;
Linlin ZHAO
1
Author Information
1. 徐州医科大学附属医院麻醉科，徐州 221006
- Publication Type:Journal Article
- Keywords:
Bupivacaine;
Liposomes;
Bibliometrics
- From:
Chinese Journal of Anesthesiology
2025;45(6):736-744
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the research trends and hotspots of bupivacaine liposomes from 1994 to 2023 using bibliometrics.Methods:A comprehensive search was conducted for the literature related to bupivacaine liposomes in the Web of Science Core Collection from 1994 to 2023. The CiteSpace software was used to conduct an in-depth analysis of the included literature data, including publication year, country, institution, author, journal, cited references, keywords, etc.Results:A total of 875 papers related to bupivacaine liposomes were included. The research and development of bupivacaine liposomes were divided into 3 stages: slow development (1994-2011), a sharp rise (2011-2021), and stabilization (2021-2023). The United States was in a leading position in terms of the number of publications, centrality, and author cooperation, and Harvard University had the largest number of publications. de Paula E had the most publications, Bramlett K had the highest number of citations, and Boogaerts J had the highest centrality of publications. Journals such as Anesthesia and Analgesia made significant contributions to this field. The most cited references focused on the infiltration of wounds and the periprosthetic injection of bupivacaine liposomes. The keyword analysis showed that local anesthetics, postoperative pain, etc. were commonly used keywords, and enhanced recovery after surgery was an emerging hotspot. Conclusions:Bupivacaine liposomes show good application prospects in the field of peripheral nerve block due to their unique pharmacological properties and safety characteristics and are expected to prolong the duration of postoperative analgesia. However, there is a difference between the actual effect and the expectation, and more clinical trials are needed to evaluate the curative effect, providing a more solid and reliable theoretical basis and practical guidance for clinical practice.
