One case of small intestinal ulcer and glomerulonephritis following COVID-19 infection
10.3760/cma.j.cn441217-20240809-00807
- VernacularTitle:新型冠状病毒感染后小肠溃疡和肾小球肾炎1例
- Author:
Sanxi AI
1
;
Shuo ZHANG
;
Wei YE
;
Yubing WEN
;
Chunlei LI
;
Wenmo HU
;
Ke ZHENG
;
Shengyu ZHANG
;
Weixun ZHOU
;
Ruijie ZHAO
;
Xuemei LI
Author Information
1. 中国医学科学院 北京协和医院肾内科，北京 100730
- Publication Type:Journal Article
- Keywords:
Intestine, small;
Ulcer;
Glomerulonephritis;
Immunoglobulin A;
Vasculitis;
SARS-CoV-2
- From:
Chinese Journal of Nephrology
2025;41(8):624-627
- CountryChina
- Language:Chinese
-
Abstract:
A 15-year-old boy developed abdominal pain and melena two weeks after COVID-19 infection, which was followed by gross hematuria and proteinuria. Laboratory studies revealed significantly elevated inflammatory markers. Endoscopic examinations showed multiple jejunal and ileal ulcers. Renal biopsy suggested mesangial proliferative glomerulonephritis with crescent formation, necrosis of capillary loops, and mesangial IgA deposits. IgA vasculitis without purpura was considered as a possible diagnosis, and the treatment with prednisone led to remission of both gastrointestinal and renal diseases.
