Construction and implementation of a new model for prevention and treatment of hepatitis B in communities in Guangzhou city
10.3760/cma.j.cn112866-20250530-00108
- VernacularTitle:广州市社区乙型肝炎防治新模式构建与实践
- Author:
Bo LI
1
;
Aiqi LU
;
Ying TAN
;
Lihua LIN
;
Songlian LIU
;
Ganqiu LIN
;
Qikai NING
;
Jiewei LIU
;
Huanhui LIANG
;
Jianping LI
;
Yujuan GUAN
Author Information
1. 广州医科大学附属市八医院肝病中心，广州 510440
- Publication Type:Journal Article
- Keywords:
Hepatitis B;
Community screening;
Diagnosis and treatment rate;
Prevention and control model
- From:
Chinese Journal of Experimental and Clinical Virology
2025;39(4):441-448
- CountryChina
- Language:Chinese
-
Abstract:
Objective:A novel grass-root community screening and management model of hepatitis B was developed in order to improve the diagnosis and treatment rate of hepatitis B in Guangzhou city.Methods:A three-tier collaborative framework［tertiary hospitals-center for disease control and prevention（CDC）-primary care clinics］implemented dual-track screening（fixed-site+mobile units）using rapid hepatitis B surface antigen（HBsAg）testing and structured surveys. Digital closed-loop management integrated screening，referral，and follow-up. Data were analyzed via SPSS 26.0.Results:Among 30 012 community-dwelling adults screened（Male∶Female=1∶1.68），overall HBsAg positive rate was 5.21%（1 565/30 012），peaking in the 50-59-year cohort（ χ2=271.80， P<0.001）. Hepatitis B knowledge awareness was critically low（39.24%）. Of 140 referred HBsAg-positive individuals，15 chronic carriers required no immediate antiviral therapy per guidelines. Treatment linkage surged from 32.8%（41/125）to 86.4%（108/125）post-intervention. aMAP hepatocellular carcinoma（HCC）risk stratification（n=82）revealed low（36.6%），intermediate（32.9%），and high-risk（30.5%）profiles. Conclusions:This coordinated，digitally-enhanced strategy significantly improved hepatitis B detection and treatment access. However，persistent knowledge gaps underscore the imperative for targeted community education and adherence support.
