Research progress in treating well-differentiated high-grade rectal neuroendocrine tu-mors
10.12354/j.issn.1000-8179.2025.20250672
- VernacularTitle:高分化高级别直肠神经内分泌肿瘤治疗的研究进展
- Author:
Lin ZI
1
;
Zhang TAO
1
;
Zhou RUI
1
Author Information
1. 重庆医科大学附属第一医院肿瘤科(重庆市 400010)
- Publication Type:Journal Article
- Keywords:
grade 3 neuroendocrine tumors(G3 NETs);
rectum;
pathological classification;
therapeutic strategies
- From:
Chinese Journal of Clinical Oncology
2025;52(15):796-800
- CountryChina
- Language:Chinese
-
Abstract:
Grade 3 neuroendocrine tumors(G3 NET)are a rare tumor subtype recently defined by WHO.They are distinct from poorly dif-ferentiated neuroendocrine carcinomas(NEC)in histopathological features,therapeutic approach,and prognosis.Due to their low incidence and the scarcity of related studies,standardized diagnostic and treatment guidelines remain incomplete.This review summarizes current evidence on rectal G3 NETs,including clinicopathological characteristics,imaging assessment methods,and major therapeutic approaches,with particular focus on management strategies for both localized and advanced disease.The aim is to provide a reference and to promote the refinement and optimization of management approaches for this uncommon tumor type.
