Risk factors for left atrial appendage thrombosis in elderly patients with non-valvular atrial fibrillation
10.3969/j.issn.1009-0126.2025.10.013
- VernacularTitle:老年非瓣膜性心房颤动患者形成左心耳血栓的危险因素分析
- Author:
Binhong TANG
1
;
Ye ZHU
;
Jia YOU
;
Xiang GU
Author Information
1. 211400 扬州,仪征市人民医院心血管内科
- Publication Type:Journal Article
- Keywords:
atrial fibrillation;
echocardiography,transesophageal;
left atrial appendage closure
- From:
Chinese Journal of Geriatric Heart Brain and Vessel Diseases
2025;27(10):1345-1348
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the risk factors of left atrial appendage(LAA)thrombosis in elderly patients with NVAF.Methods A total of 210 NVAF patients admitted to our hospital from January 2019 to June 2023 were enrolled in this study.Transesophageal echocardiography was applied used to detect the LAA thrombus,and then according to the presence or absence of thrombus,the patients were divided into a thrombus group(n=42)and a non-thrombus group(n=168).The indicators of routine blood test within 48 h of admission and the characteristics of LAA were recorded.Multivariate logistic regression analysis was performed to identify the risk factors related to the occurrence of LAA thrombus.Results The thrombus group exhibited sig-nificantly larger proportions of diabetes and nonparoxysmal AF,higher total bilirubin,increased left ventricular end-systolic diameter and left ventricular end-diastolic diameter values,and elevat-ed ratio of complex LAA,but lower INR and left ventricular ejection fraction value than the non-thrombus group(P＜0.05,P＜0.01).After adjusting for confounding factors,multivariate logistic regression analysis showed that diabetes(OR=3.585,95％CI:1.003-12.808,P=0.049)and complex LAA(OR=5.572,95％CI:2.101-14.777,P=0.001)were independent risk factors for LAA thrombosis.Conclusion LAA morphology and diabetes are independent risk factors for the occurrence of LAA thrombus in NVAF patients.
