Analysis of the current status and related factors of antiviral treatment for chronic hepatitis B virus infection in rural communities of Zhangqiu District, Jinan City
10.3760/cma.j.cn112150-20240813-00651
- VernacularTitle:济南市章丘区农村社区慢性乙型肝炎病毒感染者抗病毒治疗现状和相关因素分析
- Author:
Xiaomeng ZHANG
1
;
Bingyu YAN
;
Jingjing LYU
;
Yi FENG
;
Xin MENG
;
Chuanzhao CAO
;
Li ZHANG
Author Information
1. 山东大学公共卫生学院，济南 250012
- Publication Type:Journal Article
- Keywords:
Hepatitis B, chronic;
Therapeutic uses;
Antiviral agents
- From:
Chinese Journal of Preventive Medicine
2025;59(3):286-291
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the current status and related factors of antiviral treatment for chronic hepatitis B virus (HBV) infection in rural communities in China.Methods:In 2023, 866 chronic HBV-infected individuals from rural communities in Zhangqiu District, Jinan City, were included in the study. Basic information, disease status and antiviral treatment conditions of the infected individuals were collected through questionnaires, specimen collection and laboratory tests. Univariate and multivariate logistic regression were used to analyze the related factors of the antiviral treatment rate of those who met the indications for hepatitis B antiviral treatment.Results:The median age ( Q1, Q3) of subjects was 56 (48, 66) years old, among which 436 (50.4%) were males. There were 712 (82.2%) individuals who met the indications for hepatitis B antiviral treatment, and 110 individuals received antiviral treatment with a rate of 15.5%. Multivariate logistic regression analysis showed that compared with males, families with an average monthly income per capita of <1 000 yuan, no alcohol consumption, no smoking, and a family history of HBV infection, females ( OR=4.66, 95% CI: 2.88-7.53), families with an average monthly income per capita of 1 000-1 999 yuan ( OR=1.64, 95% CI: 1.00-2.68) and ≥2 000 yuan ( OR=2.78, 95% CI: 1.54-5.03), alcohol consumption ( OR=6.42, 95% CI: 2.80-14.7), smoking ( OR=1.98, 95% CI: 1.04-3.77), and no family history of HBV infection ( OR=1.90, 95% CI: 1.16-3.09) had a lower antiviral treatment rate for chronic HBV infection. Conclusion:The antiviral treatment rate of chronic HBV-infected individuals in rural communities of Zhangqiu District, Jinan City is low, and the related factors are female, high monthly income per capita, alcohol consumption, smoking, and no family history of HBV infection.
