Research progress of neuroelectric modulation for the treatment of inflammatory bowel disease
10.3760/cma.j.cn101480-20240719-00084
- VernacularTitle:神经电调控治疗炎症性肠病的研究进展
- Author:
Yichao ZHENG
1
;
Yueyao WU
1
;
Kehan ZHANG
1
;
Haifeng JIN
1
Author Information
1. 浙江中医药大学附属第一医院，杭州 310006
- Publication Type:Journal Article
- Keywords:
Neuromodulation;
Inflammatory bowel disease;
Electrical stimulation
- From:
Chinese Journal of Inflammatory Bowel Diseases
2025;09(3):250-254
- CountryChina
- Language:Chinese
-
Abstract:
Inflammatory bowel disease (IBD) is a chronic inflammatory disease that occurs in the gastrointestinal tract and adversely affects the quality of life of patients and the healthcare burden on society. Currently, drug therapy alone can achieve clinical remission in some patients, but it cannot break through the ceiling of what can be achieved with current therapies, and new therapeutic options still need to be found. Neuro-immunity-inflammation is closely related to each other, and the potential role of neuroelectric stimulation in modulating inflammatory response has made it a hot spot in the study of IBD treatment. However, the intrinsic mechanism of action is still unexplained and needs to be explored by further studies. This review discusses the role and mechanisms of vagus nerve electrical stimulation, sacral nerve electrical stimulation, tibial nerve electrical stimulation and other neuromodulation methods.
