A Randomized Controlled Study on the Effect of Preserving Deep Inguinal Lymph Nodes on Postoperative Lower Limb Lymphedema in Early Gynecological Malignancies
10.3969/j.issn.1009-6604.2025.09.001
- VernacularTitle:保留腹股沟深淋巴结对早期妇科恶性肿瘤术后下肢淋巴水肿的随机对照研究
- Author:
Guo YE
1
;
Zhongyong WEN
1
;
Wei CHEN
1
;
Hao HUANG
1
Author Information
1. 华南理工大学附属第六医院 佛山市南海区人民医院妇科,佛山 528200
- Publication Type:Journal Article
- Keywords:
Deep inguinal lymph node;
Lower limb lymphedema;
Pelvic lymph node clearance
- From:
Chinese Journal of Minimally Invasive Surgery
2025;25(9):513-517
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore whether preserving deep inguinal lymph nodes during surgery for early cervical cancer,endometrial cancer,and ovarian cancer can reduce postoperative lower limb lymphedema.Methods Under a prospective randomized controlled study design,100 cases of early cervical cancer,endometrial cancer,and ovarian cancer from July 2022 to July 2023 were included and randomly divided into a preservation group(preserving deep inguinal lymph nodes,n=50)and a resection group(removing deep inguinal lymph nodes,n=50).All the radical surgeries were performed by the same surgical team.The lower limb lymphedema was assessed at 1,2,6,and 12 months postoperatively,by using the Gynecologic Cancer Lymphedema Questionnaire(GCLQ)and lower limb circumference measurement.Results The incidence of lower limb lymphedema in the preservation group was 6％(3/50),significantly lower than the 20％(10/50)in the resection group(x2=4.332,P=0.037),and the onset time was later[(5.3±3.1)months vs.(2.3±1.6)months,t=2.394,P=0.036].There was no significant difference in the staging and location of lower limb lymphedema between the two groups(P＞0.05).Conclusion Preservation of deep inguinal lymph nodes during surgery for early cervical cancer,endometrial cancer,and ovarian cancer can significantly reduce the incidence of postoperative lower limb lymphedema.
