Application of intestinal ultrasound in evaluating ulcerative colitis endoscopic activity
10.3760/cma.j.cn101480-20231208-00078
- VernacularTitle:肠道超声在评估溃疡性结肠炎内镜活动中的应用
- Author:
Miaomiao PENG
1
;
Tian PU
;
Yan LI
;
Xiao HE
;
Ye ZHAO
Author Information
1. 郑州大学第一附属医院消化内科，郑州 450052
- Publication Type:Journal Article
- Keywords:
Ulcerative colitis;
Intestinal ultrasound;
Endoscopic activity;
Evaluation
- From:
Chinese Journal of Inflammatory Bowel Diseases
2024;08(6):429-433
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the accuracy of intestinal ultrasound (IUS) in evaluating endoscopic activity of ulcerative colitis (UC) .Methods:A cross-sectional survey study was conducted. Consecutive patients with UC at the First Affiliated Hospital of Zhengzhou University were recruited from June 2022 to September 2023. All the patients underwent IUS and colonoscopy. The colorectal segments were divided into remission and activity groups based on the Mayo endoscopic score (MES). The differences in IUS parameters between the remission and activity groups were compared. The accuracy of IUS parameters in diagnosing UC endoscopic activity was discussed.Results:A total of 315 colorectal segments from 80 patients were enrolled, including 171 colorectal segments in the remission group, and 144 were in the activity group. Compared with the colorectal segments in the activity group, bowel wall thicknessc (BWT) [2.40 (1.90, 3.50) mm vs. 4.70 (3.50, 6.00) mm, P < 0.001], colour doppler signal (CDS) ≥2 (5.8% vs.49.3%, P < 0.001), fatty wrapping (14.0% vs. 50.7%, P < 0.001), presence of lymph nodes (4.1% vs. 23.6%, P < 0.001), abnormal wall layer stratification (14.6% vs. 60.4%, P < 0.001) were significantly lower in the remission group. ROC curve showed that the sensitivity of BWT, CDS, fatty wrapping, presence of lymph nodes, and abnormal wall layer stratification assessment of endoscopic activity was 77.8%, 49.3%, 50.7%, 23.6%, and 60.4%, while the specificity was 74.3%, 94.2%, 86.0%, 95.9% and 85.4% respectively. Conclusion:IUS demonstrates favorable accuracy in assessing the endoscopic activity of UC, BWT, CDS, wall layer stratification, fatty wrapping, presence of lymph nodes are crucial parameters for evaluating endoscopic activity in UC.
