Strategies for glucocorticoids withdrawal in lupus nephritis: based on current evidence

VernacularTitle:狼疮肾炎治疗中糖皮质激素撤减策略：基于现有证据的汇总
Author: Jiamei QIU ¹ ; Guobin SU ; Jianwen YU ; Haijing HOU
Author Information

1. 中医证候全国重点实验室、中医药广东省实验室、广东省中医药防治难治性慢病重点实验室、广东省中医院、广州中医药大学第二临床医学院肾病科　中医药大数据研究团队，广州　510120
Publication Type:Journal Article
Keywords: Lupus nephritis; Glucocorticoids; Drug tapering; Evidence
From: Chinese Journal of Nephrology 2025;41(5):380-388
CountryChina
Language:Chinese
Abstract: Glucocorticoid therapy constitutes an essential and pivotal element in the management of lupus nephritis. Nevertheless, prolonged administration of glucocorticoids may result in systemic toxicities that adversely affect patients' quality of life and elevate mortality rates. Currently, there is a lack of definitive guidelines regarding the timing and methodologies for glucocorticoid tapering. This article aims to summarise the current evidence on glucocorticoid tapering strategies for lupus nephritis from various guidelines and studies to provide enhanced references for clinical practice.