Research progress of intestinal stricture of inflammatory bowel disease
10.3760/cma.j.cn101480-20231115-00062
- VernacularTitle:炎症性肠病肠道狭窄的治疗进展
- Author:
Yupei SHAO
1
;
Jiaming QIAN
1
;
Hong LYU
1
Author Information
1. 中国医学科学院 北京协和医学院 北京协和医院消化内科，北京 100730
- Publication Type:Journal Article
- Keywords:
Inflammatory bowel disease;
Crohn′s disease;
Ulcerative colitis;
Intestinal stricture;
Intestinal fibrosis
- From:
Chinese Journal of Inflammatory Bowel Diseases
2024;08(3):246-249
- CountryChina
- Language:Chinese
-
Abstract:
Intestinal stenosis is a common complication of inflammatory bowel disease (IBD) . Over 50% of Crohn′s disease (CD) patients develop to stricturing or penetrating phenotypes within 20 years of diagnosis. In ulcerative colitis (UC) patients, the incidence of stenosis varies from 2% to 11%. The occurrence of stenosis serves as an independent risk factor for surgery in CD and increases the risk of cancer in UC. Despite the increasing administration of biologic therapies, the progression from inflammatory phenotype to complicated phenotype has not decreased. This review summarizes the recent advances in the management of intestinal stricture in IBD, aiming to provide new insights.
