Advances in research on intestinal fibrosis in Crohn′s disease
- VernacularTitle:克罗恩病肠道纤维化的研究进展
- Author:
Yidong CHEN
1
;
Junrong LI
1
;
Xiaopeng ZHANG
1
;
Shuang LI
1
;
Yiyu CHENG
1
;
Xiaoyu FU
1
;
Jiamin LI
1
;
Liangru ZHU
1
Author Information
- Publication Type:Journal Article
- Keywords: Crohn′s disease; Intestinal fibrosis; Signaling pathways; Treatment strategies
- From: Chinese Journal of Inflammatory Bowel Diseases 2024;08(3):242-245
- CountryChina
- Language:Chinese
- Abstract: Intestinal fibrosis in Crohn′s disease (CD) presents a significant clinical challenge, imposing a substantial burden on patients, their families and society. This article explores the histopathological and pathophysiological changes associated with intestinal fibrosis, providing a detailed summary of the related phenomena and processes. Additionally, we discuss the methods for detecting and assessing intestinal fibrosis, including radiological examinations, histopathological investigations, and the application of serum biomarkers. Finally, we delve into the therapeutic strategies for intestinal fibrosis in CD and the challenges faced in this realm, offering vital insights for further research and treatment of the disease.
