Research progress of intestinal microecology as therapeutic target for inflammatory bowel disease
10.3760/cma.j.cn101480-20240820-00095
- VernacularTitle:靶向肠道微生态的炎症性肠病治疗进展
- Author:
Mengze XING
1
;
Zhen HE
Author Information
1. 中山大学附属第六医院普通外科（结直肠外科），广州 510655
- Publication Type:Journal Article
- Keywords:
Inflammatory bowel disease;
Intestinal microecology;
Fecal microbiota transplantation;
Probiotics;
Prebiotics;
Diet;
Bacteriophage
- From:
Chinese Journal of Inflammatory Bowel Diseases
2024;08(5):350-357
- CountryChina
- Language:Chinese
-
Abstract:
Inflammatory bowel disease (IBD) is a chronic inflammatory disease, which is primarily treated with medication. However, the insufficient efficacy and safety risk of current immunoregulatory therapies mean that finding new adjuvant or alternative therapies is urgently needed. As a new therapeutic target, intestinal microecology occupies an important position in the occurrence and development of IBD and is expected to play a pivotal role in the next generation of IBD therapy. Currently, fecal microbiota transplantation, probiotic therapy, prebiotic therapy, dietary therapy and bacteriophage therapy have been used to regulate the intestinal microecology of IBD. This article reviews the research progress of intestinal microecology regulation in the treatment of IBD.
