The impact of remnant cholesterol on the risk of carotid atherosclerotic plaques in elderly individuals with normal LDL-C levels
10.3969/j.issn.1673-9701.2025.25.006
- VernacularTitle:残余胆固醇对正常LDL-C老年人群颈动脉粥样硬化斑块风险的影响
- Author:
Li WANG
1
;
Zhiyang WU
1
Author Information
1. 泉州市中医院心病科,福建泉州 362000
- Publication Type:Journal Article
- Keywords:
Remnant cholesterol;
Low density lipoprotein cholesterol;
Carotid artery atherosclerotic plaques;
Atherosclerotic cardiovascular disease
- From:
China Modern Doctor
2025;63(25):24-27,31
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effect of remnant cholesterol(RC)levels on carotid atherosclerotic plaque risk in elderly individuals with normal low density lipoprotein cholesterol(LDL-C).Methods A total of 753 elderly individuals with normal LDL-C levels who were examined at Quanzhou Hospital of Traditional Chinese Medicine from March 2017 to January 2023 were included in the study.They were divided into low RC group and high RC group according to the RC levels.Kaplan-Meier risk curves were constructed,and the Cox proportional hazards regression model was used to analyze the risk factors for the occurrence of carotid atherosclerotic plaques.Results During the follow-up period,the risk of plaque occurrence in high RC group was significantly higher than that in low RC group(P＜0.001).Cox proportional hazards regression analysis showed that age,gender,RC levels and glycated hemoglobin were independent influencing factors for carotid atherosclerotic plaque.After comprehensive adjustment for confounding factors,the independent predictive effect of RC levels on the risk of carotid atherosclerotic plaque remained significant.Conclusion Elevated RC increases the risk of carotid artery atherosclerotic plaques in elderly individuals with normal LDL-C levels.
