Research progress of inflammatory bowel disease-associated bronchiectasis
10.3760/cma.j.cn101480-20240207-00020
- VernacularTitle:炎症性肠病相关支气管扩张的研究进展
- Author:
Xiaoming CHEN
1
;
Suwang WANG
;
Zhaoyuan XU
;
Lichun WANG
;
Kouxing ZHANG
;
Lei CHEN
Author Information
1. 中山大学附属第六医院呼吸与危重症医学科，广州 510655
- Publication Type:Journal Article
- Keywords:
Bronchiectasis;
Inflammatory bowel disease;
Immune regulation;
Microecological imbalance;
Lung-gut axis
- From:
Chinese Journal of Inflammatory Bowel Diseases
2024;08(4):304-308
- CountryChina
- Language:Chinese
-
Abstract:
The pulmonary complications associated with inflammatory bowel disease (IBD) predominantly affect the airways, with bronchiectasis being the most frequently observed condition. Concurrently, there is a notable increase in the prevalence of IBD among individuals with pulmonary disorders. This trend suggests a possible reciprocal relationship between IBD and pulmonary diseases, indicative of the "gut-lung axis" at play. The etiology of bronchiectasis in the context of IBD remains elusive, and there is a dearth of effective clinical tools for monitoring and prevention. This paper delves into the pathogenesis of IBD-related bronchiectasis, with a particular emphasis on the role of the gut-lung axis in this scenario. It scrutinizes the impact of immune responses and dysbiosis of the microbiome on the chronic inflammation observed in both the intestinal tract and the respiratory system.
