Clinical characteristics of pertussis in children in a tertiary hospital in Hanzhong City from 2023 to 2024
10.3760/cma.j.cn112150-20250226-00142
- VernacularTitle:2023—2024年汉中市某医院儿童百日咳病例的临床特征分析
- Author:
Suqin BAI
1
;
Yihai GU
1
;
Xiaobo LI
1
Author Information
1. 三二〇一医院微生物免疫检验科，汉中 723000
- Publication Type:Journal Article
- Keywords:
Pertussis;
Children;
Nucleic acid testing;
Clinical characteristics
- From:
Chinese Journal of Preventive Medicine
2025;59(11):1873-1876
- CountryChina
- Language:Chinese
-
Abstract:
To clarify the epidemiological characteristics of pertussis in children in Hanzhong during the nationwide surge in pertussis, this study retrospectively collected nucleic acid testing data of 4 565 children with pertussis from a tertiary hospital in Hanzhong City from September 2023 to August 2024, and collected demographic and clinical information of confirmed cases for analysis. The results showed that among 4 565 cases tested, there were 1 224 positive cases for pertussis nucleic acid testing, with a total positive rate of 26.81%. Since September 2023, the number of tests and positive cases had continuously increased, reaching a peak in May 2024, with 1 174 samples tested and 319 positive cases. Notably, the number of confirmed cases from April to July 2024 accounted for 82.03% (1 004/1 224) of the total confirmed cases during the study period. Among the 1 224 confirmed cases of pertussis, there were 647 male patients (52.86%) and 577 female patients (47.14%). The highest proportion of cases was found in school-age and preschool children, accounting for 88.81% (1 087/1 224). Among outpatients, school-age and preschool children accounted for 93.44% (897/960), while inpatient cases were mainly preschool, school-age children, and infants (94.32%, 249/264). The positive detection rates of outpatient and inpatient children in the same age group were compared. Except for the infant group, the positive rates of the other four groups were higher than those of the inpatient group (all P<0.05). Among 264 hospitalized children with pertussis, 70 cases (26.52%, 70/264) were infected with Bordetella pertussis alone, and 194 cases (73.48%, 194/264) had co-infections with other pathogens. Rhinovirus, Mycoplasma pneumoniae, and Staphylococcus aureus were the most common pathogens in co-infections.
