Research progress of regulated cell death in inflammatory bowel disease
10.3760/cma.j.cn101480-20230221-00024
- VernacularTitle:调节性细胞死亡在炎症性肠病中的研究进展
- Author:
Xizhuang GAO
1
;
Yonghong YANG
;
Wei YU
;
Fengqin ZHU
;
Guangxi ZHOU
Author Information
1. 济宁医学院临床医学院，济宁 272067
- Publication Type:Journal Article
- Keywords:
Inflammatory bowel disease;
Regulated cell death;
Autophagy;
Ferroptosis;
Pyroptosis;
Apoptosis;
Necroptosis
- From:
Chinese Journal of Inflammatory Bowel Diseases
2023;07(4):365-370
- CountryChina
- Language:Chinese
-
Abstract:
Inflammatory bowel disease (IBD) is a chronic intestinal inflammatory disease, mainly including ulcerative colitis (UC) and Crohn′s disease (CD). With the in-depth study of the role of regulated cell death (RCD) in IBD, more and more evidences show that autophagy, ferroptosis, pyroptosis, apoptosis and necroptosis are closely related to the progress and prognosis of IBD. This article reviews the pathogenesis and therapeutic prospects of RCD represented by autophagy in IBD, providing a reference for the treatment of IBD.
