Research progress of melatonin-mediated intestinal microbiota metabolism and mucosal immunity in the treatment of enteritis
10.3760/cma.j.cn101480-20221107-00180
- VernacularTitle:褪黑素介导的肠道菌群代谢及黏膜免疫在肠炎治疗中的研究进展
- Author:
Beibei LIN
1
;
Yu ZHANG
1
;
Wenluo ZHANG
1
;
Yue LEI
1
;
Mengque XU
1
Author Information
1. 浙江大学医学院附属邵逸夫医院消化内科，杭州 310016
- Publication Type:Journal Article
- Keywords:
Melatonin;
Intestinal microbiota;
Mucosal immunity;
Inflammatory bowel disease;
Enteritis
- From:
Chinese Journal of Inflammatory Bowel Diseases
2023;07(4):342-345
- CountryChina
- Language:Chinese
-
Abstract:
Melatonin is an amine hormone with high content in gastrointestinal tract, which plays a positive role in anti-inflammatory, antioxidant and other aspects. Intestinal microbiota imbalance and intestinal immune damage caused by enteritis are often accompanied by a decrease in endogenous melatonin. Supplementation of melatonin may improve intestinal microbiota disregulation and immune damage of intestinal mucosa. This article reviews the progress of melatonin-mediated microbiota metabolism and intestinal immune in the treatment of enteritis.
